Screening
The Quest for new Bioactives
Our screening partners in life science engage in the fields of infectious diseases, neurodegenerative or inflammatory diseases as well as regenerative medicine or the emergence and treatment of cancer, to name just a few. Access to a wide range of methodologies, like high-throughput screenings, macromolecular crystallography or in-silico modelling is provided by our partners.
The Molecule Archive offers different solutions to meet the needs and requirements of your screening setup and testing system regarding the size of the selection, the format, the physical state of the compounds and the target specificities.
Library Size
- Small-sized libaries (< 100 compounds) or single compounds
- Medium-sized libraries (> 100 compounds)
- Entire libary of all 12,000 compounds
Library Format
- Single tubes e.g. Eppendorf tubes
- SBS-standard microplates in 96- and 384- formats
- Special formats e.g. ECHO qualified microplates
- Assay ready plates
Physical State
- 10 mM DMSO solutions (also higher if needed)
- Dry substance
Compound Selection
- Diversity-based (clustering)
- Similarity-based (2D/3D similarity)
- Virtual Screening
Our Life Science Screening Network

KIT Karlsruhe, Institute of Functional Interfaces:
- Ute Schepers:
3D Tissue Engineering, Organ-targeted Drug Delivery
KIT Karlsruhe, Institute for Biological and Chemical Interfaces - Biologial Information Processing:
- Andrew Cato:
Androgen Receptor Signaling - Ravindra Peravali:
Zebrafish Morphological/Behavioral Screenings
KIT Karlsruhe, Institute for Chemical and Biological Interfaces - Functional Molecular Systems:
- Pavel Levkin:
Diverse Screenings on Droplet Microarrays
University of Heidelberg
- Annika Guse:
Mechanisms of Endosymbiosis, Phagocytosis, Immunity, Metabolism and Adaption to Environment - Thomas Holstein:
Stem Cell Biology and Regeneration - Steffen Lemke:
Molecular Mechanisms of Intercellular Communication - Suat Özbek:
Evolution of Extracellular Matrix and Signaling Molecules
Leibniz Lung Center Borstel
- Norbert Reiling: Identification of Anti-Mycobacterial Pathways and Therapeutics
- Ulrich Schaible: Characterization of Interactions between M. tuberculosis and Host Cells
Go To
Technical University Darmstadt, Department of Chemistry
- Katja Schmitz:
Identification of Chemokine-Receptor Ligands
Max Planck Institute of Molecular Cell Biology and Genetics Dresden (MPI-CBG)
- Anna Dubrovska
Cancer Stem Cell Biology and Epigenetics - Rico Barsacchi:
High-Throughput Assay Development
Medical School Hannover, Helmholtz Centre for Infection Research (HZI)
- Thomas Pietschmann:
Antiviral Drug Discovery and Development
Research Center Jülich, Institute of Neuroscience and Medicine
- Paolo Carloni and Giuliana Rossetti:
Computational Design of Neuroactive Drugs
University of Heidelberg, Medical Faculty Mannheim
- Jonathan Sleeman:
Regulation of Metastasis and Development of Anti-Cancer Therapies
LMU Munich
- Oliver Keppler:
Pathology of HIV Infections and Development of Therapies - Daniel Merk:
Medicinal Chemistry of Nuclear Receptor Ligands
University of Kaiserslautern
- Jörg Fahrer:
DNA Damage Response and DNA Repair Pathways, Mechanisms of Colorectal Cancer
University of Greifswald
- Ulrike Garscha:
Anti-Inflammatory Properties/ Lipid Mediator Biosynthesis in Primary and Cancer Cells
Go To
University of Mainz
- Tanja Schirmeister:
Medicinal Chemistry of Human, Viral and Parasitic Proteases and RNA Methyltransferase
University of Bonn
- Christa Müller:
Medicinal Chemistry of Purinergic Receptors, GPCRs and Ectonucleotidases
Helmholtz-Zentrum Berlin, Department of Photon Science
- Manfred Weiss:
Macromolecular Crystallography of Proteins and Protein-Ligand-Complexes
Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)
- Jens von Kries:
High-Throughput Screening Platform with variuos Assays
Universitätsklinikum Jena, Institute of Human Genetics
- Aria Baniahmad:
Mechanisms of Therapy Resistance Formation in Prostate Cancer Cells
Meet our Partners in Life Sciences
Germany
Wolfgang
Fecke
Manfred Weiss
Jens von Kries
Christa Müller
Ulrich Schaible
Institution
Norbert Reiling
Institution
Katja Schmitz
Institution
Sonja Sievers
Institution
Anna Dubrovska
Dresden University of Technology
Institution
Research Group
Small-scale single assays
Dresden
Rico Barsacchi
Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Technology Development Studio (TDS)
Institution
Bernd Fiebich
University Hospital Freiburg, Klinik für Psychiatrie und Psychotherapie
Institution
Ulrike Garscha
University of Greifswald, Institute of Pharmacy
Institution
Thomas Pietschmann
Institution
Steffen Lemke
Institution
Suat Özbek
Institution
Thomas Holstein
Institution
Annika Guse
Institution
Aria Baniahmad
University Hospital of Jena, Institute of Human Genetics
Institution
Jena
Paolo Carloni and Giulia Rossetti
Institution
Jörg Fahrer
Institution
Ute Schepers
Andrew Cato
Institution
Pavel Levkin
Institution
Ravindra Peravali
Institution
Thomas Mayer
Institution
Tanja Schirmeister
Institution
Jonathan Sleeman
Institution
Oliver Keppler
Institution
Daniel Merk
Institution
International
Jennifer Keiser
Institution
Johannes Zuegg
Institution
Steven Cobb
Institution
Kelly Chibale
University of Cape Town, Drug Discovery and Development Centre (H3D)
Institution
Luca Grumolato
Institution
Become a Life Science Screening Partner
You have become interested and want to participate as a screening partner and get compounds?
Feel free to contact us via our homepage or directly through mail or by phone. For more information, have a look under Contact.
Leave us a message!
Or choose one of these ways to contact us:
compound-platform@ioc.kit.edu
+49 721 608 23087
Karlsruhe Institute of Technology (KIT)
Institute of Biological and Chemical Systems (IBCS)
Compound Platform (ComPlat)
Hermann-von-Helmholtz-Platz 1
Building 319, room 405-443
76344 Eggenstein-Leopoldshafen
Germany
